The Effects of Intraspinal Injection of Magnesium Salts upon Tetanus
نویسندگان
چکیده
Intraspinal injections of magnesium sulphate, in doses which do not affect the respiratory centre or other vital function, are capable of abolishing completely all clonic convulsions and tonic contractions in cases of human tetanus, and experimental tetanus in monkeys. The relaxing effects of the injections may last twenty-four hours or longer. In experimental tetanus in monkeys early intraspinal injections of magnesium salts are capable of retarding the progress and development of the tetanic symptoms.
منابع مشابه
The Control of Strychnine Convulsions by Intraspinal Injections of Magnesium Sulphate
We feel that the results obtained in the human case and in our animal experiments justify the supposition that magnesium sulphate may be of use in controlling cases of poisoning by strychnine. It is a method easily available not only in large hospitals but in private practice, and requires no elaborate technique. The amount of magnesium sulphate to be used should follow the advice of Meltzer (1...
متن کاملThe Effect of a High Magnesium Intake on Calcium Retention by Swine.’
The experiment to be described in this paper relates to the influence which the addition of magnesium salts and of magnesium salts plus phosphates to the diet may exert upon calcium metabolism. They may also be interpreted as throwing some light upon the general problem of the mutual relationships which exist among the mineral constituents of the diet, considered from the standpoint of animal n...
متن کاملThe Relationship of Toxin and Antitoxin Injection Site to Tetanus Development in the Rat
The pattern of development of symptoms was studied following injection of 3 MLD (minimum lethal dose) of tetanus toxin in each of the following sites in the rat: vein, muscle, endoneurium, epineurium, spinal cord, subarachnoid space, and subdural space. Similar observations were made when 3 MPD (minimum protective dose) of antitoxin were injected into each of the above sites a few minutes after...
متن کاملCardiovascular Effects of Potassium, Calcium, Magnesium, and Barium
Therapeutic application of the specific pharmacological properties of certain cations has been made frequently. Intravenous injection of calcium chloride has long been used for the relief of certain types of tetany;'8 magnesium sulfate injections have been widely employed in the relief of convulsions;2 it has been stated that the injection of magnesium salts may control certain cardiac arrhythm...
متن کاملRestorative Effect of Salts of Magnesium and Calcium after Lethal Doses of Sodium Oxalate
The experiments presented in this paper brought out the following facts. Intramuscular injections of sodium oxalate into rabbits in doses of 0.18 and 0.2 gm. proved to be invariably fatal, death generally occurring in a comparatively short time. The symptoms consisted in excitation and tonic and clonic convulsions of diminishing strength if death was delayed. Some animals succumbed in the first...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- The Journal of Experimental Medicine
دوره 8 شماره
صفحات -
تاریخ انتشار 2003